Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis

Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous system. Foxp3(+) regulatory T (Treg) cells are reduced in frequency and dysfunctional in patients with MS, but the underlying mechanisms of this deficiency are unclear. Here, we show that induction of human IFN-γ(...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Kimura, Kimitoshi, Hohjoh, Hirohiko, Fukuoka, Masashi, Sato, Wakiro, Oki, Shinji, Tomi, Chiharu, Yamaguchi, Hiromi, Kondo, Takayuki, Takahashi, Ryosuke, Yamamura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750223/
https://ncbi.nlm.nih.gov/pubmed/29295981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02406-2
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares