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Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation

Induction of eomesodermin-positive CD4(+) T cells (Eomes(+) T helper [Th] cells) has recently been correlated with the transition from an acute stage to a later stage of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis. Moreover, these cells’ pathogenic role ha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Chenyang, Raveney, Ben J. E., Hohjoh, Hirohiko, Tomi, Chiharu, Oki, Shinji, Yamamura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800326/
https://ncbi.nlm.nih.gov/pubmed/31570595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906438116
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