JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis

Regulatory B cells, also well-known as IL-10-producing B cells, play a role in the suppression of inflammatory responses. However, the epigenetic modulation of regulatory B cells is largely unknown. Recent studies showed that the bromodomain and extra-terminal domain (BET) protein inhibitor JQ1 cont...

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Publicado en:BMB Rep
Main Authors: Lee, Min Bum, Lee, Jun-Ho, Hong, Seong Hwi, You, Jueng Soo, Nam, Seung Taek, Kim, Hyun Woo, Park, Young Hwan, Lee, Dajeong, Min, Keun Young, Park, Yeong-Min, Kim, Young Mi, Kim, Hyuk Soon, Choi, Wahn Soo
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749911/
https://ncbi.nlm.nih.gov/pubmed/29187284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.12.194
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