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Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
Eukaryotic cells contain an elegant protein quality control system that is crucial in maintaining cellular homeostasis; however, dysfunction of this system results in endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR). Severe or prolonged ER stress is associated...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749533/ https://ncbi.nlm.nih.gov/pubmed/29293089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93560 |
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