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Endoplasmic reticulum stress in the pathogenesis of fibrotic disease

Eukaryotic cells contain an elegant protein quality control system that is crucial in maintaining cellular homeostasis; however, dysfunction of this system results in endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR). Severe or prolonged ER stress is associated...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Kropski, Jonathan A., Blackwell, Timothy S.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749533/
https://ncbi.nlm.nih.gov/pubmed/29293089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93560
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