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Endoplasmic Reticulum Stress in Disease Pathogenesis
The endoplasmic reticulum (ER) is the site of synthesis and folding of membrane and secretory proteins, which, collectively, represent a large fraction of the total protein output of a mammalian cell. Therefore, the protein flux through the ER must be carefully monitored for abnormalities, including...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653419/ https://ncbi.nlm.nih.gov/pubmed/18039139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pathmechdis.3.121806.151434 |
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