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Endoplasmic Reticulum Stress in Disease Pathogenesis

The endoplasmic reticulum (ER) is the site of synthesis and folding of membrane and secretory proteins, which, collectively, represent a large fraction of the total protein output of a mammalian cell. Therefore, the protein flux through the ER must be carefully monitored for abnormalities, including...

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Autors principals: Lin, Jonathan H., Walter, Peter, Yen, T.S. Benedict
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653419/
https://ncbi.nlm.nih.gov/pubmed/18039139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pathmechdis.3.121806.151434
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