γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program

γδT cells produce inflammatory cytokines and have been implicated in the pathogenesis of cancer, infectious diseases, and autoimmunity. The T cell receptor (TCR) signal transduction that specifically regulates the development of IL-17–producing γδT (γδT17) cells largely remains unclear. Here, we sho...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Muro, Ryunosuke, Nitta, Takeshi, Nakano, Kenta, Okamura, Tadashi, Takayanagi, Hiroshi, Suzuki, Harumi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749532/
https://ncbi.nlm.nih.gov/pubmed/29202478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95837
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