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γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program
γδT cells produce inflammatory cytokines and have been implicated in the pathogenesis of cancer, infectious diseases, and autoimmunity. The T cell receptor (TCR) signal transduction that specifically regulates the development of IL-17–producing γδT (γδT17) cells largely remains unclear. Here, we sho...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749532/ https://ncbi.nlm.nih.gov/pubmed/29202478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95837 |
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