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TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
The murine thymus produces discrete γδ T cell subsets making either interferon-γ (IFN--γ) or interleukin 17 (IL-17), but the role of the TCR in this developmental process remains controversial. Here we show that mice haploinsufficient for both Cd3g and Cd3d (CD3DH, for CD3 double haploinsufficient)...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Immunol |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875770/ https://ncbi.nlm.nih.gov/pubmed/27043412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3424 |
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