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Epigenetic and transcriptional signatures of the stable and plastic differentiation of proinflammatory γδ T-cell subsets
Two distinct subsets of γδ T cells that produce interleukin 17 (IL-17) (CD27(−) γδ T cells) or interferon-γ (IFN-γ) (CD27(+) γδ T cells) develop in the mouse thymus, but the molecular determinants of their functional potential in the periphery remain unknown. Here we conducted a genome-wide characte...
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| Publié dans: | Nat Immunol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834994/ https://ncbi.nlm.nih.gov/pubmed/23995235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2702 |
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