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Epigenetic and transcriptional signatures of the stable and plastic differentiation of proinflammatory γδ T-cell subsets

Two distinct subsets of γδ T cells that produce interleukin 17 (IL-17) (CD27(−) γδ T cells) or interferon-γ (IFN-γ) (CD27(+) γδ T cells) develop in the mouse thymus, but the molecular determinants of their functional potential in the periphery remain unknown. Here we conducted a genome-wide characte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Immunol
Egile Nagusiak: Schmolka, Nina, Serre, Karine, Grosso, Ana R, Rei, Margarida, Pennington, Daniel J, Gomes, Anita Q, Silva-Santos, Bruno
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834994/
https://ncbi.nlm.nih.gov/pubmed/23995235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2702
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