Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression()

Genome-wide association studies (GWAS) have been successful in facilitating the understanding of genetic architecture behind human diseases, but this approach faces many challenges. To identify disease-related loci with modest to weak effect size, GWAS requires very large sample sizes, which can be...

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Udgivet i:Pac Symp Biocomput
Main Authors: Li, Binglan, Verma, Shefali S., Veturi, Yogasudha C., Verma, Anurag, Bradford, Yuki, Haas, David W., Ritchie, Marylyn D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749400/
https://ncbi.nlm.nih.gov/pubmed/29218904
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