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Cis-SNPs Set Testing and PrediXcan Analysis for Gene Expression Data using Linear Mixed Models
Understanding the functional mechanism of SNPs identified in GWAS on complex diseases is currently a challenging task. The studies of expression quantitative trait loci (eQTL) have shown that regulatory variants play a crucial role in the function of associated SNPs. Detecting significant genes (cal...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681585/ https://ncbi.nlm.nih.gov/pubmed/29127305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15055-8 |
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