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Testing SNPs and sets of SNPs for importance in association studies
A major goal of genetic association studies concerned with single nucleotide polymorphisms (SNPs) is the detection of SNPs exhibiting an impact on the risk of developing a disease. Typically, this problem is approached by testing each of the SNPs individually. This, however, can lead to an inaccurat...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006123/ https://ncbi.nlm.nih.gov/pubmed/20601626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq042 |
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