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Implications of human genetic variation on CRISPR-based therapeutic genome editing
CRISPR-Cas genome editing methods hold immense potential as therapeutic tools to fix disease-causing mutations at the level of DNA. In contrast to typical drug development strategies aimed at targets that are highly conserved among individual patients, treatment of disease at the genomic level must...
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| Vydáno v: | Nat Med |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749234/ https://ncbi.nlm.nih.gov/pubmed/28759051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4377 |
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