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CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors

The development of clustered regularly interspaced short-palindromic repeat (CRISPR)-based biotechnologies has revolutionized the life sciences and introduced new therapeutic modalities with the potential to treat a wide range of diseases. Here, we describe CRISPR-based strategies to improve human h...

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Pubblicato in:Cell
Autori principali: Wang, Dan, Zhang, Feng, Gao, Guangping
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236621/
https://ncbi.nlm.nih.gov/pubmed/32243786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.03.023
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