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A bioinorganic approach to fragment-based drug discovery targeting metalloenzymes
Metal-dependent enzymes (i.e. metalloenzymes) make up a large fraction of all enzymes and are critically important in a wide range of biological processes, including DNA modification, protein homeostasis, antibiotic resistance, and many others. Consequently, metalloenzymes represent a vast, and larg...
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| Publicado no: | Acc Chem Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749230/ https://ncbi.nlm.nih.gov/pubmed/28715203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00242 |
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