Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

DNA methylation is a well-known epigenetic modification that plays a crucial role in gene regulation, but genome-wide analysis of DNA methylation remains technically challenging and costly. DNA methylation-dependent restriction enzymes can be used to restrict CpG methylation analysis to methylated r...

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Bibliographic Details
Published in:Genome Res
Main Authors: Boers, Ruben, Boers, Joachim, de Hoon, Bas, Kockx, Christel, Ozgur, Zeliha, Molijn, Anco, van IJcken, Wilfred, Laven, Joop, Gribnau, Joost
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2018
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Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749185/
https://ncbi.nlm.nih.gov/pubmed/29222086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.222885.117
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