Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors

INTRODUCTION: The majority of desmoid-type fibromatosis (DTF) tumors harbor a β-catenin mutation, affecting specific codons in CTNNB1 exon 3. S45F tumors are reported to have a higher chance of recurrence after surgery and more resistance to systemic treatments compared to wild-type (WT) and T41A tu...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Timbergen, Milea J. M., Boers, Ruben, Vriends, Anne L. M., Boers, Joachim, van IJcken, Wilfred F. J., Lavrijsen, Marla, Grünhagen, Dirk J., Verhoef, Cornelis, Sleijfer, Stefan, Smits, Ron, Gribnau, Joost, Wiemer, Erik A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658920/
https://ncbi.nlm.nih.gov/pubmed/33194643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.565031
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