Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors

INTRODUCTION: The majority of desmoid-type fibromatosis (DTF) tumors harbor a β-catenin mutation, affecting specific codons in CTNNB1 exon 3. S45F tumors are reported to have a higher chance of recurrence after surgery and more resistance to systemic treatments compared to wild-type (WT) and T41A tu...

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Vydáno v:Front Oncol
Hlavní autoři: Timbergen, Milea J. M., Boers, Ruben, Vriends, Anne L. M., Boers, Joachim, van IJcken, Wilfred F. J., Lavrijsen, Marla, Grünhagen, Dirk J., Verhoef, Cornelis, Sleijfer, Stefan, Smits, Ron, Gribnau, Joost, Wiemer, Erik A. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658920/
https://ncbi.nlm.nih.gov/pubmed/33194643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.565031
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