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Buccal swab as a reliable predictor for X inactivation ratio in inaccessible tissues

BACKGROUND: As a result of the epigenetic phenomenon of X chromosome inactivation (XCI) every woman is a mosaic of cells with either an inactive paternal X chromosome or an inactive maternal X chromosome. The ratio between inactive paternal and maternal X chromosomes is different for every female in...

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Détails bibliographiques
Publié dans:J Med Genet
Auteurs principaux: de Hoon, Bas, Monkhorst, Kim, Riegman, Peter, Laven, Joop S E, Gribnau, Joost
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680131/
https://ncbi.nlm.nih.gov/pubmed/26220467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103194
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