Impact of regulatory variation across human iPSCs and differentiated cells

Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular differentiation and cell types that are otherwise difficult to access. We investigated the use of iPSCs and iPSC-derived cells to study the impact of genetic variation on gene regulation across different cell types an...

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Pubblicato in:Genome Res
Autori principali: Banovich, Nicholas E., Li, Yang I., Raj, Anil, Ward, Michelle C., Greenside, Peyton, Calderon, Diego, Tung, Po Yuan, Burnett, Jonathan E., Myrthil, Marsha, Thomas, Samantha M., Burrows, Courtney K., Romero, Irene Gallego, Pavlovic, Bryan J., Kundaje, Anshul, Pritchard, Jonathan K., Gilad, Yoav
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749177/
https://ncbi.nlm.nih.gov/pubmed/29208628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.224436.117
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