Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs

The advent of induced pluripotent stem cells (iPSCs) revolutionized human genetics by allowing us to generate pluripotent cells from easily accessible somatic tissues. This technology can have immense implications for regenerative medicine, but iPSCs also represent a paradigm shift in the study of c...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Burrows, Courtney K., Banovich, Nicholas E., Pavlovic, Bryan J., Patterson, Kristen, Gallego Romero, Irene, Pritchard, Jonathan K., Gilad, Yoav
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727884/
https://ncbi.nlm.nih.gov/pubmed/26812582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005793
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