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Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation

Apoptotic cells generated by programmed cell death are engulfed by phagocytes and enclosed within membrane-bound phagosomes. Maturation of apoptotic cell–containing phagosomes leads to formation of phagolysosomes where cell corpses are degraded. The class III phosphatidylinositol 3-kinase (PI3-kinas...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Liu, Jinchao, Li, Meijiao, Li, Lin, Chen, She, Wang, Xiaochen
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748982/
https://ncbi.nlm.nih.gov/pubmed/29092895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705116
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