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Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca(2+)/Calmodulin-PI3K hVPS34 Cascade

The capacity of Mycobacterium tuberculosis to infect latently over one billion people and cause two million fatalities annually rests with its ability to block phagosomal maturation into the phagolysosome in infected macrophages. Here we describe how M. tuberculosis toxin lipoarabinomannan (LAM) cau...

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Bibliografische gegevens
Hoofdauteurs: Vergne, Isabelle, Chua, Jennifer, Deretic, Vojo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194170/
https://ncbi.nlm.nih.gov/pubmed/12925680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030527
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