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Vps34 kinase domain dynamics regulate the autophagic PI 3-kinase complex
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) is required for the initiation of essentially all macroautophagic processes. PI3KC3-C1 consists of the lipid kinase catalytic subunit VPS34, the VPS15 scaffold, and the regulatory BECN1 and ATG14 subunits. The VPS34 catalytic domain a...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573195/ https://ncbi.nlm.nih.gov/pubmed/28757208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.003 |
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