Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

There is remarkable redundancy between the Cyclin–Cdk complexes that comprise the cell cycle machinery. None of the mammalian A-, D-, or E-type cyclins are required in development until implantation, and only Cdk1 is essential for early cell divisions. Cyclin B1 is essential for development, but whe...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Strauss, Bernhard, Harrison, Andrew, Coelho, Paula Almeida, Yata, Keiko, Zernicka-Goetz, Magdalena, Pines, Jonathon
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748970/
https://ncbi.nlm.nih.gov/pubmed/29074707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612147
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