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Delayed APC/C activation extends the first mitosis of mouse embryos

The correct temporal regulation of mitosis underpins genomic stability because it ensures the alignment of chromosomes on the mitotic spindle that is required for their proper segregation to the two daughter cells. Crucially, sister chromatid separation must be delayed until all the chromosomes have...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ajduk, Anna, Strauss, Bernhard, Pines, Jonathon, Zernicka-Goetz, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575289/
https://ncbi.nlm.nih.gov/pubmed/28851945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09526-1
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