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Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass
Ammonia is a ubiquitous by-product of cellular metabolism, however the biological consequences of ammonia production are not fully understood, especially in cancer. We find that ammonia is not merely a toxic waste product, but is recycled into central amino acid metabolism to maximize nitrogen utili...
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| Publicado no: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748897/ https://ncbi.nlm.nih.gov/pubmed/29025995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam9305 |
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