Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

The median overall survival for children with diffuse intrinsic pontine glioma (DIPG) is less than one year. The majority of diffuse midline gliomas, including more than 70% of DIPGs, harbor an amino acid substitution from lysine (K) to methionine (M) at position 27 of histone 3 variant 3 (H3.3). Fr...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Chheda, Zinal S., Kohanbash, Gary, Okada, Kaori, Jahan, Naznin, Sidney, John, Pecoraro, Matteo, Yang, Xinbo, Carrera, Diego A., Downey, Kira M., Shrivastav, Shruti, Liu, Shuming, Lin, Yi, Lagisetti, Chetana, Chuntova, Pavlina, Watchmaker, Payal B., Mueller, Sabine, Pollack, Ian F., Rajalingam, Raja, Carcaboso, Angel M., Mann, Matthias, Sette, Alessandro, Garcia, K. Christopher, Hou, Yafei, Okada, Hideho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2018
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748856/
https://ncbi.nlm.nih.gov/pubmed/29203539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171046
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