Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

The median overall survival for children with diffuse intrinsic pontine glioma (DIPG) is less than one year. The majority of diffuse midline gliomas, including more than 70% of DIPGs, harbor an amino acid substitution from lysine (K) to methionine (M) at position 27 of histone 3 variant 3 (H3.3). Fr...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chheda, Zinal S., Kohanbash, Gary, Okada, Kaori, Jahan, Naznin, Sidney, John, Pecoraro, Matteo, Yang, Xinbo, Carrera, Diego A., Downey, Kira M., Shrivastav, Shruti, Liu, Shuming, Lin, Yi, Lagisetti, Chetana, Chuntova, Pavlina, Watchmaker, Payal B., Mueller, Sabine, Pollack, Ian F., Rajalingam, Raja, Carcaboso, Angel M., Mann, Matthias, Sette, Alessandro, Garcia, K. Christopher, Hou, Yafei, Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748856/
https://ncbi.nlm.nih.gov/pubmed/29203539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171046
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