IMMU-41. H3.3K27M MUTATION-DERIVED NOVEL NEOANTIGEN – CHARACTERIZATION OF THE HLA-A2-BINDING EPITOPE AND A SPECIFIC T CELL RECEPTOR FOR DEVELOPMENT OF T CELL-BASED IMMUNOTHERAPY

The median overall survival for children with diffuse intrinsic pontine glioma (DIPG) is less than a year. The majority of diffuse midline gliomas, including over 70% of DIPG, harbor an amino-acid substitution from lysine (K) to methionine (M) at position 27 of histone 3 variant 3.3. As predicted by...

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Publicado no:Neuro Oncol
Main Authors: Chheda, Zinal, Kohanbash, Gary, Okada, Kaori, Jahan, Naznin, Sidney, John, Pecoraro, Matteo, Carrera, Diego, Shrivastav, Shruti, Liu, Shuming, Downey, Kira, Chuntova, Pavlina, Watchmaker, Payal, Mueller, Sabine, Pollack, Ian, Rajalingam, Raja, Carcaboso, Angel Montero, Mann, Matthias, Sette, Alessandro, Hou, Yafei, Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692694/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.499
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