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Variation in CYP2A6 Activity and Personalized Medicine
The cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several clinically relevant substrates, including nicotine—the primary psychoactive component in cigarette smoke. The gene that encodes the CYP2A6 enzyme is highly polymorphic, resulting in extensive interindividual variation in CYP2A6 enzyme activ...
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| Publicado no: | J Pers Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748630/ https://ncbi.nlm.nih.gov/pubmed/29194389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm7040018 |
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