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Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer

OBJECTIVES: The Northern Plains (NP) and Southwest (SW) American Indian populations differ in their smoking patterns and lung cancer incidence. We aimed to compare CYP2A6 genetic variation and CYP2A6 enzyme activity (representative of the rate of nicotine metabolism) between the two tribal populatio...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Tanner, Julie-Anne, Henderson, Jeffrey A., Buchwald, Dedra, Howard, Barbara V., Henderson, Patricia Nez, Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382092/
https://ncbi.nlm.nih.gov/pubmed/28181923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000271
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