A Computational Workflow Translates a 58-Gene Signature to a Formalin-Fixed, Paraffin-Embedded Sample-Based Companion Diagnostic for Personalized Treatment of the BRAF-Mutation-Like Subtype of Colorectal Cancers

Colorectal cancer patients with the BRAF(p.V600E) mutation have poor prognosis in metastatic setting. Personalized treatment options and companion diagnostics are needed to better treat these patients. Previously, we developed a 58-gene signature to characterize the distinct gene expression pattern...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:High Throughput
Autori principali: In’t Veld, Sjors G. J. G., Duong, Kim N., Snel, Mireille, Witteveen, Anke, Beumer, Inès J., Delahaye, Leonie J. M. J., Wehkamp, Diederik, Bernards, René, Glas, Annuska M., Tian, Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748595/
https://ncbi.nlm.nih.gov/pubmed/29479053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ht6040016
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi