A Computational Workflow Translates a 58-Gene Signature to a Formalin-Fixed, Paraffin-Embedded Sample-Based Companion Diagnostic for Personalized Treatment of the BRAF-Mutation-Like Subtype of Colorectal Cancers

Colorectal cancer patients with the BRAF(p.V600E) mutation have poor prognosis in metastatic setting. Personalized treatment options and companion diagnostics are needed to better treat these patients. Previously, we developed a 58-gene signature to characterize the distinct gene expression pattern...

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Detaylı Bibliyografya
Yayımlandı:High Throughput
Asıl Yazarlar: In’t Veld, Sjors G. J. G., Duong, Kim N., Snel, Mireille, Witteveen, Anke, Beumer, Inès J., Delahaye, Leonie J. M. J., Wehkamp, Diederik, Bernards, René, Glas, Annuska M., Tian, Sun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748595/
https://ncbi.nlm.nih.gov/pubmed/29479053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ht6040016
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