Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient‐derived spheroid cultures

Patient‐derived in vitro cultures of colorectal cancer (CRC) may help guide treatment strategies prior to patient treatment. However, most previous studies have been performed on a single biopsy per tumor. The purpose of this study was to analyze multiple spatially distinct biopsies from CRCs and se...

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Udgivet i:Mol Oncol
Main Authors: Árnadóttir, Sigrid S., Jeppesen, Maria, Lamy, Philippe, Bramsen, Jesper B., Nordentoft, Iver, Knudsen, Michael, Vang, Søren, Madsen, Mogens R., Thastrup, Ole, Thastrup, Jacob, L. Andersen, Claus
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748486/
https://ncbi.nlm.nih.gov/pubmed/29130628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12156
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