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Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer

Genetic alterations identified in adjacent normal appearing tissue in bladder cancer patients are indicative of a field disease. Here we assessed normal urothelium transformation and intra-tumour heterogeneity (ITH) in four patients with bladder cancer. Exome sequencing identified private acquired m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thomsen, Mathilde Borg Houlberg, Nordentoft, Iver, Lamy, Philippe, Vang, Søren, Reinert, Line, Mapendano, Christophe Kamungu, Høyer, Søren, Ørntoft, Torben F., Jensen, Jørgen Bjerggaard, Dyrskjøt, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600970/
https://ncbi.nlm.nih.gov/pubmed/28916750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11291-0
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