Spatial and temporal clonal evolution during development of metastatic urothelial carcinoma

Patients with metastatic bladder cancer have a median survival of only 13–14 months. Precision medicine using targeted therapy may improve survival. Here we investigated spatial and temporal tumour evolution and tumour heterogeneity in order to evaluate the potential use of targeted treatment of met...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Thomsen, Mathilde B.H., Nordentoft, Iver, Lamy, Philippe, Høyer, Søren, Vang, Søren, Hedegaard, Jakob, Borre, Michael, Jensen, Jørgen B., Ørntoft, Torben F., Dyrskjøt, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423216/
https://ncbi.nlm.nih.gov/pubmed/27582092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.08.003
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