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SUMO Modification of the RNA-Binding Protein La Regulates Cell Proliferation and STAT3 Protein Stability
The cancer-associated RNA-binding protein La is posttranslationally modified by phosphorylation and sumoylation. Sumoylation of La regulates not only the trafficking of La in neuronal axons but also its association with specific mRNAs. Depletion of La in various types of cancer cell lines impairs ce...
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| Опубликовано в: : | Mol Cell Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748460/ https://ncbi.nlm.nih.gov/pubmed/29084811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00129-17 |
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