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SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells

The RNA-binding protein La is involved in several aspects of RNA metabolism including the translational regulation of mRNAs and processing of pre-tRNAs. Besides its well-described phosphorylation by Casein kinase 2, the La protein is also posttranslationally modified by the Small Ubiquitin-like MOdi...

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Publicado en:PLoS One
Autores principales: Kota, Venkatesh, Sommer, Gunhild, Durette, Chantal, Thibault, Pierre, van Niekerk, Erna A., Twiss, Jeffery L., Heise, Tilman
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880191/
https://ncbi.nlm.nih.gov/pubmed/27224031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156365
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