Synthesis and Biological Assessment of 3,7-Dihydroxytropolones

3,7-Dihydroxytropolones (3,7-dHTs) are highly oxygenated troponoids that have been identified as lead compounds for several human diseases. To date, structure-function studies on these molecules have been limited due to a scarcity of synthetic methods for their preparation. New synthetic strategies...

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Gepubliceerd in:Org Biomol Chem
Hoofdauteurs: Hirsch, D. R., Schiavone, D. V., Berkowitz, A. J., Morrison, L. A., Masaoka, T., Wilson, J. A., Lomonosova, E., Zhao, H., Patel, B. S., Datla, S. H., Hoft, S. G., Majidi, S. J., Pal, R. K., Gallicchio, E., Tang, L., Tavis, J. E., Le Grice, S. F. J., Beutler, J. A., Murelli, R. P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748270/
https://ncbi.nlm.nih.gov/pubmed/29098212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob02453c
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