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Identification of cancer genes that are independent of dominant proliferation and lineage programs

Large, multidimensional cancer datasets provide a resource that can be mined to identify candidate therapeutic targets for specific subgroups of tumors. Here, we analyzed human breast cancer data to identify transcriptional programs associated with tumors bearing specific genetic driver alterations....

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Selfors, Laura M., Stover, Daniel G., Harris, Isaac S., Brugge, Joan S., Coloff, Jonathan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748209/
https://ncbi.nlm.nih.gov/pubmed/29229826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714877115
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