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Identification of cancer genes that are independent of dominant proliferation and lineage programs

Large, multidimensional cancer datasets provide a resource that can be mined to identify candidate therapeutic targets for specific subgroups of tumors. Here, we analyzed human breast cancer data to identify transcriptional programs associated with tumors bearing specific genetic driver alterations....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Selfors, Laura M., Stover, Daniel G., Harris, Isaac S., Brugge, Joan S., Coloff, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748209/
https://ncbi.nlm.nih.gov/pubmed/29229826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714877115
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