Protection Against a Mixed SHIV Challenge by a Broadly Neutralizing Antibody Cocktail

HIV-1 sequence diversity presents a major challenge for the clinical development of broadly neutralizing antibodies (bNAbs) for both therapy and prevention. Sequence variation in critical bNAb epitopes has been observed in the majority of HIV-1 infected individuals and can lead to viral escape follo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Julg, Boris, Liu, Po-Ting, Wagh, Kshitij, Fischer, William M., Abbink, Peter, Mercado, Noe B., Whitney, James B., Nkolola, Joseph P., McMahan, Katherine, Tartaglia, Lawrence J., Borducchi, Erica N., Khatiwada, Shreeya, Kamath, Megha, LeSuer, Jake A., Seaman, Michael S., Schmidt, Stephen D., Mascola, John R., Burton, Dennis R., Korber, Bette T., Barouch, Dan H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747528/
https://ncbi.nlm.nih.gov/pubmed/28931655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aao4235
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg