Protection Against a Mixed SHIV Challenge by a Broadly Neutralizing Antibody Cocktail

HIV-1 sequence diversity presents a major challenge for the clinical development of broadly neutralizing antibodies (bNAbs) for both therapy and prevention. Sequence variation in critical bNAb epitopes has been observed in the majority of HIV-1 infected individuals and can lead to viral escape follo...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Julg, Boris, Liu, Po-Ting, Wagh, Kshitij, Fischer, William M., Abbink, Peter, Mercado, Noe B., Whitney, James B., Nkolola, Joseph P., McMahan, Katherine, Tartaglia, Lawrence J., Borducchi, Erica N., Khatiwada, Shreeya, Kamath, Megha, LeSuer, Jake A., Seaman, Michael S., Schmidt, Stephen D., Mascola, John R., Burton, Dennis R., Korber, Bette T., Barouch, Dan H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747528/
https://ncbi.nlm.nih.gov/pubmed/28931655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aao4235
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