Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) chain. In cartilage, CS plays important roles as the main component of the extracellular matrix (ECM), existing as side chains of the major cartilage proteoglycan, aggrecan. Six glycosyltransferases are known to coordinately synthesize t...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Shimbo, Miki, Suzuki, Riku, Fuseya, Sayaka, Sato, Takashi, Kiyohara, Katsue, Hagiwara, Kozue, Okada, Risa, Wakui, Hiromasa, Tsunakawa, Yuki, Watanabe, Hideto, Kimata, Koji, Narimatsu, Hisashi, Kudo, Takashi, Takahashi, Satoru
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747463/
https://ncbi.nlm.nih.gov/pubmed/29287114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190333
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items