Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) chain. In cartilage, CS plays important roles as the main component of the extracellular matrix (ECM), existing as side chains of the major cartilage proteoglycan, aggrecan. Six glycosyltransferases are known to coordinately synthesize t...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Shimbo, Miki, Suzuki, Riku, Fuseya, Sayaka, Sato, Takashi, Kiyohara, Katsue, Hagiwara, Kozue, Okada, Risa, Wakui, Hiromasa, Tsunakawa, Yuki, Watanabe, Hideto, Kimata, Koji, Narimatsu, Hisashi, Kudo, Takashi, Takahashi, Satoru
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747463/
https://ncbi.nlm.nih.gov/pubmed/29287114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190333
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