Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) chain. In cartilage, CS plays important roles as the main component of the extracellular matrix (ECM), existing as side chains of the major cartilage proteoglycan, aggrecan. Six glycosyltransferases are known to coordinately synthesize t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shimbo, Miki, Suzuki, Riku, Fuseya, Sayaka, Sato, Takashi, Kiyohara, Katsue, Hagiwara, Kozue, Okada, Risa, Wakui, Hiromasa, Tsunakawa, Yuki, Watanabe, Hideto, Kimata, Koji, Narimatsu, Hisashi, Kudo, Takashi, Takahashi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747463/
https://ncbi.nlm.nih.gov/pubmed/29287114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190333
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