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Human α-Defensin 6: a Small Peptide that Self-Assembles and Protects the Host by Entangling Microbes

Human α-defensin 6 (HD6) is a 32-residue cysteine-rich peptide that contributes to innate immunity by protecting the host at mucosal sites. This peptide is produced in small intestinal Paneth cells as an 81-residue precursor peptide that is stored in granules, and is released into the lumen. One unu...

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Détails bibliographiques
Publié dans:Acc Chem Res
Auteurs principaux: Chairatana, Phoom, Nolan, Elizabeth M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747246/
https://ncbi.nlm.nih.gov/pubmed/28296382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00653
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