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Molecular Basis for Self-Assembly of a Human Host-Defense Peptide That Entraps Bacterial Pathogens

[Image: see text] Human α-defensin 6 (HD6) is a 32-aa cysteine-rich peptide of the innate immune system. Although HD6 is a member of an antimicrobial peptide family, it exhibits negligible antibacterial activity in vitro. Rather, HD6 possesses a unique innate immune mechanism whereby it self-assembl...

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Détails bibliographiques
Auteurs principaux: Chairatana, Phoom, Nolan, Elizabeth M.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183631/
https://ncbi.nlm.nih.gov/pubmed/25158166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5057906
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