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Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers
BACKGROUND: Enhancers are modular regulatory elements that are central to the spatial and temporal regulation of gene expression. Bidirectional transcription initiating at enhancers has been proposed to mark active enhancers and as such has been utilized to experimentally identify active enhancers d...
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| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5747114/ https://ncbi.nlm.nih.gov/pubmed/29284524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1379-8 |
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