Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers

BACKGROUND: Enhancers are modular regulatory elements that are central to the spatial and temporal regulation of gene expression. Bidirectional transcription initiating at enhancers has been proposed to mark active enhancers and as such has been utilized to experimentally identify active enhancers d...

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Detaylı Bibliyografya
Yayımlandı:Genome Biol
Asıl Yazarlar: Young, Robert S., Kumar, Yatendra, Bickmore, Wendy A., Taylor, Martin S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747114/
https://ncbi.nlm.nih.gov/pubmed/29284524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1379-8
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