Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

BACKGROUND: Epigenetic mechanisms such as chromatin accessibility impact transcription factor binding to DNA and transcriptional specificity. The androgen receptor (AR), a master regulator of the male phenotype and prostate cancer pathogenesis, acts primarily through ligand-activated transcription o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tewari, Alok K, Yardimci, Galip Gürkan, Shibata, Yoichiro, Sheffield, Nathan C, Song, Lingyun, Taylor, Barry S, Georgiev, Stoyan G, Coetzee, Gerhard A, Ohler, Uwe, Furey, Terrence S, Crawford, Gregory E, Febbo, Phillip G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491416/
https://ncbi.nlm.nih.gov/pubmed/23034120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r88
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg