Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

BACKGROUND: Epigenetic mechanisms such as chromatin accessibility impact transcription factor binding to DNA and transcriptional specificity. The androgen receptor (AR), a master regulator of the male phenotype and prostate cancer pathogenesis, acts primarily through ligand-activated transcription o...

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Autores principales: Tewari, Alok K, Yardimci, Galip Gürkan, Shibata, Yoichiro, Sheffield, Nathan C, Song, Lingyun, Taylor, Barry S, Georgiev, Stoyan G, Coetzee, Gerhard A, Ohler, Uwe, Furey, Terrence S, Crawford, Gregory E, Febbo, Phillip G
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491416/
https://ncbi.nlm.nih.gov/pubmed/23034120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r88
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